Adderall and Vyvanse both fall in the class of central nervous system suppressants. Adderall is made up of two ingredients, namely amphetamine and dextroamphetamine. The main ingredient used in Vyvanse is lisdexamfetamine. Both medicines work by balancing brain neurotransmitters that cause inattention, hyperactivity, and impulsiveness issues. A longer-acting version of Adderall, known as Adderall X.R., was launched in 2001. Adderall and Vyvanse together are known as Schedule II drugs mean they have a high risk for abuse and addiction, so a person using Adderall and Vyvanse must take precautions.