BOTOX Cosmetic is the primary FDA-permitted prescription treatment to dramatically lessen moderate to intense frown strains, crow's feet, chuckle traces, and forehead wrinkles. BOTOX is a purified protein made from the bacterium Clostridium botulinum. It temporarily works by relaxing the muscles we overuse in our facial expressions. When the muscle tissues are comfortable & relaxed with a few tiny injections of BOTOX, the strains and wrinkles are dramatically dwindled, often within days of the first treatment.